RCT- resources
Guidance
- ASSERT - A Standard for the Scientific and Ethical Review of Trials
- CONSORT - checklist and flow diagram to improve the quality of reports of randomized controlled trials
Books
Journal Articles
Why randomised controlled trials fail but needn't - Series from the Canadian Medical Association Journal
- 1. Failure to gain "coal-face" commitment and to use the uncertainty principle
- 2. Failure to employ physiological statistics, or the only formula a clinician-trialist is ever likely to need (or understand!)
Articles on Randomised Controlled Trials from the British Medical Journal
( In order to access these BMJ articles you will need to register with the BMJ as a free services user)
- Why are randomized controlled trials important?
- Treatment allocation in controlled trials: why randomise?
- How to randomise
- Randomisation methods in controlled trials
- Randomisation methods: concealment
- Randomising groups of patients
- Blinding in clinical trials and other studies
- Randomisation methods: concealment
- Baseline imbalance in randomised controlled trials
- What outcomes should be measured?
- What is meant by intention to treat analysis? Survey of published RCTs
- Cost effectiveness calculations and sample size
- Analysis of a trial randomised in clusters
- Analysing controlled trials with baseline and follow up measurements
- Crossover trials
- Understanding controlled trials: What are pragmatic trials?
- What is a patient preference trial?
- What is Zelen's design?
- When placebo controlled trials are essential and equivalence trials are inadequate
- Ethical issues in the design and conduct of cluster randomised controlled trials
Other Resources
- Clinical Trial Simulator - Free Software package to explore aspect of RCTs
- Clinical Trials tool kit - Practical guide for UK clinical trials
- Randomization Generator - Create a randomization plan
- STATS - STeve's Attempt to Teach Statistics
Page last edited: 23 February 2010
